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Aktuella publikationer vid institutionen

  • Aftab, O. (2014). Label free high throughput screening for apoptosis inducing chemicals using time-lapse microscopy signal processing.. Apoptosis (London) DOI Mer information
  • Murray, C., Ortblad, K., Guinovart, C., Lim, S., Wolock, T. et al. (2014). Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013.. The Lancet Epub ahead of print. DOI Mer information
  • Rönn, M., Lind, L., Orberg, J., Kullberg, J., Söderberg, S. et al. (2014). Bisphenol A is related to circulating levels of adiponectin, leptin and ghrelin, but not to fat mass or fat distribution in humans.. Chemosphere, 112: 42-8 DOI Mer information
  • Lovdahl, S., Henriksson, K., Baghaei, F., Holmstrom, M., Berntorp, E. et al. (2014). A longitudinal study of family structure in Swedish persons with haemophilia. Haemophilia, 20(4): 493-499 DOI Mer information

PIVUS - Prospective Investigation of the Vasculature in Uppsala Seniors

The PIVUS study started in 2001 with the primary aim to investigate the predicive power of different measurements of endothelial function and arterial compliance in a random sample of 1000 subjects aged 70 living in the community of Uppsala. As secondary aims, the study also included measurements of cardiac function and structure by ultrasound and MRI, evaluation of atherosclerosis by ultrasound and MRI, 7 day food intake recordings, detailed ECG analysis, cardiovascular autonomic function, body composition by DXA, DNA analysis and lung function, as well as a number of biochemical markers.

The inclusion of subjects in the study was completed in June 2004 by the team below:

 
          Anna Stenborg, Kerstin Marttala, Lars Lind, Jan Hall

In March 2006 a reinvesigation of the cohort at the age of 75 was started. The major measurements performed at age 70 will be repeated at age 75. In addition, we will focus on infarcts in the brain and heart, so both of these items will be investigated by brain and myocardial MRI in all subjects. Also cognitive tests are included in the reinvestigation that was completed in September 2009.Of the initial 1016 subjects, 52 had died during the 5 years and 827 attended the re-examination at age 75.

In the spring of 2011 we started the 80-year reinvestigation of the cohort. This round will continue until the summer of 2014 and we expect that 500-600 of the original sample will attend. We measure the traditional CV risk factors, 2 cognitive function tests, ultrasound of the carotid arteries and the heart, a DXA scan and an MRI scan of the brain and abdominal region.