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Stulna celler gjorde Henrietta Lacks odödlig

Historien om Henrietta Lacks, vars livmoderhalstumör gav upphov till de odödliga HeLa cellerna, vilka sedan bidragit till vacciner, nobelpris och att i väsentliga drag lösa cancerns gåta. Förre vicerektorn Ulf Pettersson och Anders Bergqvist (forskare vid IMV) har medverkat i detta ämne i vetenskapsradion

One Health Sweden

One Health konferens i Bangkok

”A world united against infectious diseases: cross-sectoral solutions” var temat på den andra internationella One Health-konferensen som gick av stapeln i månadsskiftet januari/februari i Bangkok. Representanter från IEE – One Health Sweden från SVA, SLU och Uppsala universitet fanns på plats

Vart tionde astmafall har samband med jobbet

Faktorer på jobbet ligger bakom ungefär vart tionde fall av astma som bryter ut i vuxen ålder. – Yrkesastma har varit ett nästan bortglömt problem under senare år, men våra resultat visar att det i många jobb fortfarande finns brister i arbetsmiljön som kan ge upphov till astma, säger professor Christer Janson i en artikel i UNT

  • Lönnberg, M., Garle, M., Lönnberg, L., Birgegård, G. (2013). Patients with anaemia can shift from kidney to liver production of erythropoietin as shown by glycoform analysis. Journal of Pharmaceutical and Biomedical Analysis, 81-€“82(0): 187-192 [DOI] [More information]
  • Emilsson, L., Carlsson, R., James, S., Ludvigsson, J. (2013). Letter: coeliac disease and ischaemic heart disease - a true additional risk factor? Authors' reply. Alimentary Pharmacology and Therapeutics, 37(11): 1118-1118 [DOI] [More information]
  • Arnlov, J., Carlsson, A., Sundström, J., Ingelsson, E., Larsson, A. et al. (2013). Serum FGF23 and Risk of Cardiovascular Events in Relation to Mineral Metabolism and Cardiovascular Pathology. American Society of Nephrology. Clinical Journal, 8(5): 781-786 [DOI] [More information]
  • Lind, Y., Lind, M., Salihovic, S., van Bavel, B., Lind, L. (2013). Circulating levels of persistent organic pollutants (POPs) are associated with left ventricular systolic and diastolic dysfunction in the elderly. Environmental Research, 123: 39-45 [DOI] [Free fulltext] [More information]

PIVUS - Prospective Investigation of the Vasculature in Uppsala Seniors

The PIVUS study started in 2001 with the primary aim to investigate the predicive power of different measurements of endothelial function and arterial compliance in a random sample of 1000 subjects aged 70 living in the community of Uppsala. As secondary aims, the study also included measurements of cardiac function and structure by ultrasound and MRI, evaluation of atherosclerosis by ultrasound and MRI, 7 day food intake recordings, detailed ECG analysis, cardiovascular autonomic function, body composition by DXA, DNA analysis and lung function, as well as a number of biochemical markers.

The inclusion of subjects in the study was completed in June 2004 by the team below:

 
          Anna Stenborg, Kerstin Marttala, Lars Lind, Jan Hall

In March 2006 a reinvesigation of the cohort at the age of 75 was started. The major measurements performed at age 70 will be repeated at age 75. In addition, we will focus on infarcts in the brain and heart, so both of these items will be investigated by brain and myocardial MRI in all subjects. Also cognitive tests are included in the reinvestigation that was completed in September 2009.Of the initial 1016 subjects, 52 had died during the 5 years and 827 attended the re-examination at age 75.

In the spring of 2011 we started the 80-year reinvestigation of the cohort. This round will continue until the summer of 2014 and we expect that 500-600 of the original sample will attend. We measure the traditional CV risk factors, 2 cognitive function tests, ultrasound of the carotid arteries and the heart, a DXA scan and an MRI scan of the brain and abdominal region.

MRI angiography, supplied by Håkan Ahlström and Lars Johansson, Dept. of Radiology