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The PIVUS study started in 2001 with the
primary aim to investigate the predicive power of different
measurements of endothelial function and arterial compliance
in a random sample of 1000 subjects aged 70 living in the
community of Uppsala.
As secondary aims, the study also included measurements of
cardiac function and structure by ultrasound and MRI,
evaluation of atherosclerosis by ultrasound and MRI, 7 day
food intake recordings, detailed ECG analysis,
cardiovascular autonomic function, body composition by DXA,
DNA analysis and lung function, as well as a number of
biochemical markers.
The inclusion of subjects in the study was completed in June
2004 by the team below: |
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In March 2006 a reinvesigation of the cohort
at the age of 75 was started. The major measurements
performed at age 70 will be repeated at age 75. In addition,
we will focus on infarcts in the brain and heart, so both of
these items will be investigated by brain and myocardial MRI
in all subjects. Also cognitive tests are included in the
reinvestigation that is planned to continue to June 2009.
The MRI angiography at top was supplied by
Håkan Ahlström and Lars Johansson, Department of Radiology. |
