Publikationer från Cancerfarmakologi och beräkningsmedicin
Här visas de 50 senaste publikationerna från forskargruppen Cancerfarmakologi och beräkningsmedicin.
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Assessment in vitro of interactions between anti-cancer drugs and noncancer drugs commonly used by cancer patients
Ingår i Anti-Cancer Drugs, s. 92-102, 2023.
Artikel i tidskrift
DOI för Assessment in vitro of interactions between anti-cancer drugs and noncancer drugs commonly used by cancer patients Ladda ner fulltext (pdf) av Assessment in vitro of interactions between anti-cancer drugs and noncancer drugs commonly used by cancer patients
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Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress
Ingår i NATURE CANCER, s. 156-, 2022.
Artikel i tidskrift
DOI för Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress Ladda ner fulltext (pdf) av Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress
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Higher levels of neurofilament light chain and total tau in CSF are associated with negative outcome after shunt surgery in patients with normal pressure hydrocephalus
Ingår i Fluids and Barriers of the CNS, 2022.
Artikel i tidskrift
DOI för Higher levels of neurofilament light chain and total tau in CSF are associated with negative outcome after shunt surgery in patients with normal pressure hydrocephalus Ladda ner fulltext (pdf) av Higher levels of neurofilament light chain and total tau in CSF are associated with negative outcome after shunt surgery in patients with normal pressure hydrocephalus
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Ek, Frida
Vilande cancerceller: Tredimensionella cellmodeller för utvärdering av nya cancerläkemedel
2022.
Licentiatavhandling, sammanläggning
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Immune-Proteome Profiling in Classical Hodgkin Lymphoma Tumor Diagnostic Tissue
Ingår i Cancers, 2022.
Artikel i tidskrift
DOI för Immune-Proteome Profiling in Classical Hodgkin Lymphoma Tumor Diagnostic Tissue Ladda ner fulltext (pdf) av Immune-Proteome Profiling in Classical Hodgkin Lymphoma Tumor Diagnostic Tissue
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Lysophophatidylcholine 16:0 mediates chronic joint pain associated to rheumatic diseases through acid-sensing ion channel 3
Ingår i Pain, s. 1999-2013, 2022.
Artikel i tidskrift
DOI för Lysophophatidylcholine 16:0 mediates chronic joint pain associated to rheumatic diseases through acid-sensing ion channel 3 Ladda ner fulltext (pdf) av Lysophophatidylcholine 16:0 mediates chronic joint pain associated to rheumatic diseases through acid-sensing ion channel 3
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Selective radiosensitization by nitazoxanide of quiescent clonogenic colon cancer tumour cells
Ingår i Oncology Letters, 2022.
Artikel i tidskrift
DOI för Selective radiosensitization by nitazoxanide of quiescent clonogenic colon cancer tumour cells Ladda ner fulltext (pdf) av Selective radiosensitization by nitazoxanide of quiescent clonogenic colon cancer tumour cells
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Ilixadencel, a Cell-based Immune Primer, plus Sunitinib Versus Sunitinib Alone in Metastatic Renal Cell Carcinoma: A Randomized Phase 2 Study
Ingår i European Urology Open Science, s. 38-45, 2022.
Artikel i tidskrift
DOI för Ilixadencel, a Cell-based Immune Primer, plus Sunitinib Versus Sunitinib Alone in Metastatic Renal Cell Carcinoma: A Randomized Phase 2 Study Ladda ner fulltext (pdf) av Ilixadencel, a Cell-based Immune Primer, plus Sunitinib Versus Sunitinib Alone in Metastatic Renal Cell Carcinoma: A Randomized Phase 2 Study
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Cell-lineage controlled epigenetic regulation in glioblastoma stem cells determines functionally distinct subgroups and predicts patient survival
Ingår i Nature Communications, 2022.
Artikel i tidskrift
DOI för Cell-lineage controlled epigenetic regulation in glioblastoma stem cells determines functionally distinct subgroups and predicts patient survival Ladda ner fulltext (pdf) av Cell-lineage controlled epigenetic regulation in glioblastoma stem cells determines functionally distinct subgroups and predicts patient survival
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Sorafenib and nitazoxanide disrupt mitochondrial function and inhibit regrowth capacity in three-dimensional models of hepatocellular and colorectal carcinoma
Ingår i Scientific Reports, 2022.
Artikel i tidskrift
DOI för Sorafenib and nitazoxanide disrupt mitochondrial function and inhibit regrowth capacity in three-dimensional models of hepatocellular and colorectal carcinoma Ladda ner fulltext (pdf) av Sorafenib and nitazoxanide disrupt mitochondrial function and inhibit regrowth capacity in three-dimensional models of hepatocellular and colorectal carcinoma
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Plasma protein biomarker profiling reveals major differences between acute leukaemia, lymphoma patients and controls
Ingår i New Biotechnology, s. 21-29, 2022.
Artikel i tidskrift
DOI för Plasma protein biomarker profiling reveals major differences between acute leukaemia, lymphoma patients and controls Ladda ner fulltext (pdf) av Plasma protein biomarker profiling reveals major differences between acute leukaemia, lymphoma patients and controls
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Single-cell transcriptional pharmacodynamics of trifluridine in a tumor-immune model
Ingår i Scientific Reports, 2022.
Artikel i tidskrift
DOI för Single-cell transcriptional pharmacodynamics of trifluridine in a tumor-immune model Ladda ner fulltext (pdf) av Single-cell transcriptional pharmacodynamics of trifluridine in a tumor-immune model
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Metabolomics: The Stethoscope for the Twenty-First Century
Ingår i Medical principles and practice, s. 301-310, 2021.
Artikel i tidskrift
DOI för Metabolomics: The Stethoscope for the Twenty-First Century Ladda ner fulltext (pdf) av Metabolomics: The Stethoscope for the Twenty-First Century
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Multi‐cohort profiling reveals elevated CSF levels of brain‐enriched proteins in Alzheimer’s disease
Ingår i Annals of Clinical and Translational Neurology, s. 1456-1470, 2021.
Artikel i tidskrift
DOI för Multi‐cohort profiling reveals elevated CSF levels of brain‐enriched proteins in Alzheimer’s disease Ladda ner fulltext (pdf) av Multi‐cohort profiling reveals elevated CSF levels of brain‐enriched proteins in Alzheimer’s disease
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Different Inflammatory Signatures in Alzheimer's Disease and Frontotemporal Dementia Cerebrospinal Fluid
Ingår i Journal of Alzheimer's Disease, s. 629-640, 2021.
Artikel i tidskrift
DOI för Different Inflammatory Signatures in Alzheimer's Disease and Frontotemporal Dementia Cerebrospinal Fluid Ladda ner fulltext (pdf) av Different Inflammatory Signatures in Alzheimer's Disease and Frontotemporal Dementia Cerebrospinal Fluid
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Melphalan flufenamide inhibits osteoclastogenesis by suppressing proliferation of monocytes
Ingår i Bone Reports, 2021.
Artikel i tidskrift
DOI för Melphalan flufenamide inhibits osteoclastogenesis by suppressing proliferation of monocytes
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Increased levels of plasma cytokines and correlations to organ failure and 30-day mortality in critically ill Covid-19 patients
Ingår i Cytokine, 2021.
Artikel i tidskrift
DOI för Increased levels of plasma cytokines and correlations to organ failure and 30-day mortality in critically ill Covid-19 patients Ladda ner fulltext (pdf) av Increased levels of plasma cytokines and correlations to organ failure and 30-day mortality in critically ill Covid-19 patients
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Conditions for maintenance of hepatocyte differentiation and function in 3D cultures
Ingår i iScience, 2021.
Artikel i tidskrift
DOI för Conditions for maintenance of hepatocyte differentiation and function in 3D cultures Ladda ner fulltext (pdf) av Conditions for maintenance of hepatocyte differentiation and function in 3D cultures
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DNA Methylation Signatures Predict Cytogenetic Subtype and Outcome in Pediatric Acute Myeloid Leukemia (AML)
Ingår i Genes, 2021.
Artikel i tidskrift
DOI för DNA Methylation Signatures Predict Cytogenetic Subtype and Outcome in Pediatric Acute Myeloid Leukemia (AML) Ladda ner fulltext (pdf) av DNA Methylation Signatures Predict Cytogenetic Subtype and Outcome in Pediatric Acute Myeloid Leukemia (AML)
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A phase 2a clinical study on the safety and efficacy of individualized dosed mebendazole in patients with advanced gastrointestinal cancer
Ingår i Scientific Reports, 2021.
Artikel i tidskrift
DOI för A phase 2a clinical study on the safety and efficacy of individualized dosed mebendazole in patients with advanced gastrointestinal cancer Ladda ner fulltext (pdf) av A phase 2a clinical study on the safety and efficacy of individualized dosed mebendazole in patients with advanced gastrointestinal cancer
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Challenging conventional karyotyping by next-generation karyotyping in 281 intensively treated patients with AML
Ingår i Blood Advances, s. 1003-1016, 2021.
Artikel i tidskrift
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Plasma proteome profiling of cardiotoxicity in patients with diffuse large B-cell lymphoma
Ingår i Cardio-Oncology, 2021.
Artikel i tidskrift
DOI för Plasma proteome profiling of cardiotoxicity in patients with diffuse large B-cell lymphoma Ladda ner fulltext (pdf) av Plasma proteome profiling of cardiotoxicity in patients with diffuse large B-cell lymphoma
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Metabolic drift in the aging nervous system is reflected in human cerebrospinal fluid
Ingår i Scientific Reports, 2021.
Artikel i tidskrift
DOI för Metabolic drift in the aging nervous system is reflected in human cerebrospinal fluid Ladda ner fulltext (pdf) av Metabolic drift in the aging nervous system is reflected in human cerebrospinal fluid
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Toll-like receptor 4 methylation grade is linked to depressive symptom severity
Ingår i Translational Psychiatry, 2021.
Artikel i tidskrift
DOI för Toll-like receptor 4 methylation grade is linked to depressive symptom severity Ladda ner fulltext (pdf) av Toll-like receptor 4 methylation grade is linked to depressive symptom severity
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[New recommendation on pharmacogenetic screening prior to 5-fluorouracil based cancer treatment - Swedish experience indicates less adverse effects and healthcare cost savings].
Ingår i Läkartidningen, 2021.
Artikel i tidskrift
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Approaches for containerized scientific workflows in cloud environments with applications in life science
Ingår i F1000 Research, s. 513-513, 2021.
Artikel i tidskrift
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COVIDENZA - A prospective, multicenter, randomized PHASE II clinical trial of enzalutamide treatment to decrease the morbidity in patients with Corona virus disease 2019 (COVID-19): a structured summary of a study protocol for a randomised controlled trial
Ingår i Trials, 2021.
Artikel i tidskrift
DOI för COVIDENZA - A prospective, multicenter, randomized PHASE II clinical trial of enzalutamide treatment to decrease the morbidity in patients with Corona virus disease 2019 (COVID-19): a structured summary of a study protocol for a randomised controlled trial Ladda ner fulltext (pdf) av COVIDENZA - A prospective, multicenter, randomized PHASE II clinical trial of enzalutamide treatment to decrease the morbidity in patients with Corona virus disease 2019 (COVID-19): a structured summary of a study protocol for a randomised controlled trial
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Mebendazole is unique among tubulin-active drugs in activating the MEK-ERK pathway
Ingår i Scientific Reports, 2020.
Artikel i tidskrift
DOI för Mebendazole is unique among tubulin-active drugs in activating the MEK-ERK pathway Ladda ner fulltext (pdf) av Mebendazole is unique among tubulin-active drugs in activating the MEK-ERK pathway
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Targeting aggressive osteosarcoma with a peptidase-enhanced cytotoxic melphalan flufenamide
Ingår i THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY, 2020.
Artikel i tidskrift
DOI för Targeting aggressive osteosarcoma with a peptidase-enhanced cytotoxic melphalan flufenamide Ladda ner fulltext (pdf) av Targeting aggressive osteosarcoma with a peptidase-enhanced cytotoxic melphalan flufenamide
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Chantzi, Efthymia
Algorithmic discovery, development and personalized selection of higher-order drug cocktails: A label-free live-cell imaging & secretomics approach
2020.
Doktorsavhandling, sammanläggning
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COMBSecretomics: a pragmatic methodological framework for higher-order drug combination analysis using secretomics
Ingår i PLOS ONE, 2020.
Artikel i tidskrift
DOI för COMBSecretomics: a pragmatic methodological framework for higher-order drug combination analysis using secretomics Ladda ner fulltext (pdf) av COMBSecretomics: a pragmatic methodological framework for higher-order drug combination analysis using secretomics
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Rational Design of Azastatin as a Potential ADC Payload with Reduced Bystander Killing.
Ingår i ChemMedChem, s. 2500-2512, 2020.
Artikel i tidskrift
DOI för Rational Design of Azastatin as a Potential ADC Payload with Reduced Bystander Killing. Ladda ner fulltext (pdf) av Rational Design of Azastatin as a Potential ADC Payload with Reduced Bystander Killing.
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Gene Expression Alterations during Development of Castration-Resistant Prostate Cancer Are Detected in Circulating Tumor Cells
Ingår i Cancers, 2020.
Artikel i tidskrift
DOI för Gene Expression Alterations during Development of Castration-Resistant Prostate Cancer Are Detected in Circulating Tumor Cells Ladda ner fulltext (pdf) av Gene Expression Alterations during Development of Castration-Resistant Prostate Cancer Are Detected in Circulating Tumor Cells
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Genomic and transcriptomic features of dermatofibrosarcoma protuberans: Unusual chromosomal origin of the COL1A1-PDGFB fusion gene and synergistic effects of amplified regions in tumor development
Ingår i Cancer Genetics, s. 34-41, 2020.
Artikel i tidskrift
DOI för Genomic and transcriptomic features of dermatofibrosarcoma protuberans: Unusual chromosomal origin of the COL1A1-PDGFB fusion gene and synergistic effects of amplified regions in tumor development Ladda ner fulltext (pdf) av Genomic and transcriptomic features of dermatofibrosarcoma protuberans: Unusual chromosomal origin of the COL1A1-PDGFB fusion gene and synergistic effects of amplified regions in tumor development
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Antibacterial pyrrolidinyl and piperidinyl substituted 2,4-diacetylphloroglucinols from Pseudomonas protegens UP46
Ingår i Journal of antibiotics (Tokyo. 1968), s. 739-747, 2020.
Artikel i tidskrift
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Association between proteomics and obstructive sleep apnea phenotypes in a community-based cohort of women
Ingår i Journal of Sleep Research, 2020.
Artikel i tidskrift
DOI för Association between proteomics and obstructive sleep apnea phenotypes in a community-based cohort of women Ladda ner fulltext (pdf) av Association between proteomics and obstructive sleep apnea phenotypes in a community-based cohort of women
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Prognostic Value of Circulating Microvesicle Subpopulations in Ischemic Stroke and TIA
Ingår i Translational Stroke Research, s. 708-719, 2020.
Artikel i tidskrift
DOI för Prognostic Value of Circulating Microvesicle Subpopulations in Ischemic Stroke and TIA Ladda ner fulltext (pdf) av Prognostic Value of Circulating Microvesicle Subpopulations in Ischemic Stroke and TIA
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Microparticles expressing myeloperoxidase as potential biomarkers in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV)
Ingår i Journal of Molecular Medicine, s. 1279-1286, 2020.
Artikel i tidskrift
DOI för Microparticles expressing myeloperoxidase as potential biomarkers in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) Ladda ner fulltext (pdf) av Microparticles expressing myeloperoxidase as potential biomarkers in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV)
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A Novel Multiplex Based Platform for Osteoarthritis Drug Candidate Evaluation
Ingår i Annals of Biomedical Engineering, s. 2438-2448, 2020.
Artikel i tidskrift
DOI för A Novel Multiplex Based Platform for Osteoarthritis Drug Candidate Evaluation
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Isopedopeptins A-H: Cationic Cyclic Lipodepsipeptides from Pedobacter cryoconitis UP508 Targeting WHO Top-Priority Carbapenem-Resistant Bacteria
Ingår i ACS Chemical Biology, s. 2937-2944, 2020.
Artikel i tidskrift
DOI för Isopedopeptins A-H: Cationic Cyclic Lipodepsipeptides from Pedobacter cryoconitis UP508 Targeting WHO Top-Priority Carbapenem-Resistant Bacteria Ladda ner fulltext (pdf) av Isopedopeptins A-H: Cationic Cyclic Lipodepsipeptides from Pedobacter cryoconitis UP508 Targeting WHO Top-Priority Carbapenem-Resistant Bacteria
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Changes in the plasma microvesicle proteome during the ovarian hyperstimulation phase of assisted reproductive technology
Ingår i Scientific Reports, 2020.
Artikel i tidskrift
DOI för Changes in the plasma microvesicle proteome during the ovarian hyperstimulation phase of assisted reproductive technology Ladda ner fulltext (pdf) av Changes in the plasma microvesicle proteome during the ovarian hyperstimulation phase of assisted reproductive technology
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Melflufen for relapsed and refractory multiple myeloma
Ingår i Expert Opinion on Investigational Drugs, s. 1069-1078, 2020.
Artikel i tidskrift
DOI för Melflufen for relapsed and refractory multiple myeloma
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Elevated inflammatory proteins in cerebrospinal fluid from patients with painful knee osteoarthritis are associated with reduced symptom severity
Ingår i Journal of Neuroimmunology, 2020.
Artikel i tidskrift
DOI för Elevated inflammatory proteins in cerebrospinal fluid from patients with painful knee osteoarthritis are associated with reduced symptom severity Ladda ner fulltext (pdf) av Elevated inflammatory proteins in cerebrospinal fluid from patients with painful knee osteoarthritis are associated with reduced symptom severity
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Descriptive Proteome Analysis to Investigate Context-Dependent Treatment Responses to OXPHOS Inhibition in Colon Carcinoma Cells Grown as Monolayer and Multicellular Tumor Spheroids
Ingår i ACS Omega, s. 17242-17254, 2020.
Artikel i tidskrift
DOI för Descriptive Proteome Analysis to Investigate Context-Dependent Treatment Responses to OXPHOS Inhibition in Colon Carcinoma Cells Grown as Monolayer and Multicellular Tumor Spheroids Ladda ner fulltext (pdf) av Descriptive Proteome Analysis to Investigate Context-Dependent Treatment Responses to OXPHOS Inhibition in Colon Carcinoma Cells Grown as Monolayer and Multicellular Tumor Spheroids
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Phosphatidylserine positive microparticles improve hemostasis in in-vitro hemophilia A plasma models
Ingår i Scientific Reports, 2020.
Artikel i tidskrift
DOI för Phosphatidylserine positive microparticles improve hemostasis in in-vitro hemophilia A plasma models Ladda ner fulltext (pdf) av Phosphatidylserine positive microparticles improve hemostasis in in-vitro hemophilia A plasma models
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Mebendazole-induced M1 polarisation of THP-1 macrophages may involve DYRK1B inhibition
Ingår i BMC Research Notes, 2019.
Artikel i tidskrift
DOI för Mebendazole-induced M1 polarisation of THP-1 macrophages may involve DYRK1B inhibition Ladda ner fulltext (pdf) av Mebendazole-induced M1 polarisation of THP-1 macrophages may involve DYRK1B inhibition
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COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining
Ingår i BMC Bioinformatics, 2019.
Artikel i tidskrift
DOI för COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining Ladda ner fulltext (pdf) av COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining
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Anti-inflammatory drugs with more penetration into the central nervous system may contribute to the treatment of trigeminal neuralgia Reply
Ingår i Pain, s. 2898-2899, 2019.
Artikel i tidskrift
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Cerebrospinal fluid biomarkers of inflammation in trigeminal neuralgia patients operated with microvascular decompression
Ingår i Pain, s. 2603-2611, 2019.
Artikel i tidskrift
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Circulating Levels of Interferon Regulatory Factor-5 Associates With Subgroups of Systemic Lupus Erythematosus Patients.
Ingår i Frontiers in Immunology, 2019.
Artikel i tidskrift
DOI för Circulating Levels of Interferon Regulatory Factor-5 Associates With Subgroups of Systemic Lupus Erythematosus Patients. Ladda ner fulltext (pdf) av Circulating Levels of Interferon Regulatory Factor-5 Associates With Subgroups of Systemic Lupus Erythematosus Patients.