Research at the Department of Medical Sciences
At the department the research performed comprises both basic studies on causative mechanisms of disease and clinical applications such as improved diagnosis and methods of treatment. In support there are a number of technology platforms and other resources. The research is mainly conducted within six Research Areas.
Circulation and respiration
Within this broad area the researchers work with cardiovascular and respiratory diseases, but also with sleep and the impact of various environmental factors for health in a wider perspective.
Many studies are done as national and international collaborations. By experimental and epidemiological studies researchers can identify risk factors and by clinical trials and registry studies both existing and new therapies are evaluated for their efficiency.
Research groups - Research group leaders:
- Occupational and environmental medicine - Magnus Swartengren
- Cardiology - Bertil Lindahl
- Cardiologi-arrythmia - Carina Blomström
- Cardiovascular epidemiology - Lars Lind
- Clinical physiologi - Andrei Malinovschi, acting
- Respiratory, allergy and sleep research - Christer Jansson
- Molecular epidemiology - Tove Fall
Infections by bacteria, viruses and fungi is a major cause of disease globally and new epidemics and pandemics emerge repeatedly. To, if possible, block the arisal of such we study zoonotic diseases using a multidisciplinary approach. We also work with improvement of vaccines. Another important theme is antimicrobial resistance where we are engaged in multiple parallel projects and initiatives.
Research groups-Research group leaders
Inflammation is an important component of many diseases that cause significant morbidity and mortality. These include autoimmune diseases such as a number of rheumatoid diseases, kidney diseases, inflammatory bowel diseases and cutaneous diseases. The research unit strive to dissect the mechanisms of disease, to improve diagnosis and to develop new treatments.
Research groups-research group leaders
Within this area several independent research groups are working to identify risk factors for, and the aetiology of, several common diseases such as cancer, diabetes and osteoporosis. State of the art genomics, epigenetics and computational modelling methods are employed together with in vitro experiments, utilizing biological materials in the form of cells, DNA, protein or metabolites to uncover casual links between environment, heredity and disease. High throughput experimental techniques are also used to develop therapies for cancer and other complex diseases.
Research groups - Research group leaders
Research in the field of endocrinology is performed by three research groups focused on strategies for treatment of diabetes, obesity and metabolic bone diseases. Can novel drugs targeting adipose tissue metabolism be used for prevention and treatment of type 2 diabetes?”, “Can stem cells be used to treat type 1 diabetes?”, “What causes metabolic bone diseases?” are examples of questions that are addressed. A large number of different methods are used in our studies, mostly with human subjects, and they include clinical trials.
Research Groups and Research group leaders
Hematology and Oncology
Haematological diseases and neuroendocrine tumours are in focus for a number of research groups that are in the cancer research at the department. The approach is broad and includes basic studies on the aetiology for cancer. New drugs and treatments are developed and evaluated both in vitro and in clinical trials.