Department of Medical Sciences

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Publications from Cancer Pharmacology and Computational Medicine

These are the 50 most recent publications from the research group Cancer Pharmacology and Computational Medicine.

Assessment in vitro of interactions between anti-cancer drugs and noncancer drugs commonly used by cancer patients

Andersson, Claes; Ye, Jiawei; Blom, Kristin; Fryknäs, Mårten et al.

Part of Anti-Cancer Drugs, p. 92-102, 2023.

Article in journal

DOI for Assessment in vitro of interactions between anti-cancer drugs and noncancer drugs commonly used by cancer patients Download full text (pdf) of Assessment in vitro of interactions between anti-cancer drugs and noncancer drugs commonly used by cancer patients

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Phenotypic screening platform identifies statins as enhancers of immune cell-induced cancer cell death

Selvin, Tove; Berglund, Malin; Lenhammar, Lena; Jarvius, Malin et al.

Part of BMC Cancer, 2023.

Article in journal

DOI for Phenotypic screening platform identifies statins as enhancers of immune cell-induced cancer cell death Download full text (pdf) of Phenotypic screening platform identifies statins as enhancers of immune cell-induced cancer cell death

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Ex vivo assessment of cancer drug sensitivity in epithelial ovarian cancer and its association with histopathological type, treatment history and clinical outcome

Bjersand, Kathrine; Blom, Kristin; Sundström Poromaa, Inger; Stålberg, Karin et al.

Part of International Journal of Oncology, 2022.

Article in journal

DOI for Ex vivo assessment of cancer drug sensitivity in epithelial ovarian cancer and its association with histopathological type, treatment history and clinical outcome Download full text (pdf) of Ex vivo assessment of cancer drug sensitivity in epithelial ovarian cancer and its association with histopathological type, treatment history and clinical outcome

Open access
Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

Bonagas, Nadilly; Gustafsson, Nina M. S.; Henriksson, Martin; Marttila, Petra et al.

Part of NATURE CANCER, p. 156-, 2022.

Article in journal

DOI for Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress Download full text (pdf) of Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

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Higher levels of neurofilament light chain and total tau in CSF are associated with negative outcome after shunt surgery in patients with normal pressure hydrocephalus

Braun, Madelen; Bjurnemark, Caroline; Seo, Woosung; Freyhult, Eva et al.

Part of Fluids and Barriers of the CNS, 2022.

Article in journal

DOI for Higher levels of neurofilament light chain and total tau in CSF are associated with negative outcome after shunt surgery in patients with normal pressure hydrocephalus Download full text (pdf) of Higher levels of neurofilament light chain and total tau in CSF are associated with negative outcome after shunt surgery in patients with normal pressure hydrocephalus

Open access
Ek, Frida

Quiescent cancer cells: Three-dimensional cell models for evaluation of new therapeutics

2022.

Licentiate thesis, comprehensive summary

Download full text (pdf) of Ek, Frida

Open access
Immune-Proteome Profiling in Classical Hodgkin Lymphoma Tumor Diagnostic Tissue

Gholiha, Alex R.; Hollander, Peter; Löf, Liza; Larsson, Anders et al.

Part of Cancers, 2022.

Article in journal

DOI for Immune-Proteome Profiling in Classical Hodgkin Lymphoma Tumor Diagnostic Tissue Download full text (pdf) of Immune-Proteome Profiling in Classical Hodgkin Lymphoma Tumor Diagnostic Tissue

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Lysophophatidylcholine 16:0 mediates chronic joint pain associated to rheumatic diseases through acid-sensing ion channel 3

Jacquot, F.; Khoury, S.; Labrum, B.; Delanoe, K. et al.

Part of Pain, p. 1999-2013, 2022.

Article in journal

DOI for Lysophophatidylcholine 16:0 mediates chronic joint pain associated to rheumatic diseases through acid-sensing ion channel 3 Download full text (pdf) of Lysophophatidylcholine 16:0 mediates chronic joint pain associated to rheumatic diseases through acid-sensing ion channel 3

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Selective radiosensitization by nitazoxanide of quiescent clonogenic colon cancer tumour cells

Karlsson, Henning; Fryknäs, Mårten; Senkowski, Wojciech; Larsson, Rolf et al.

Part of Oncology Letters, 2022.

Article in journal

DOI for Selective radiosensitization by nitazoxanide of quiescent clonogenic colon cancer tumour cells Download full text (pdf) of Selective radiosensitization by nitazoxanide of quiescent clonogenic colon cancer tumour cells

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Ilixadencel, a Cell-based Immune Primer, plus Sunitinib Versus Sunitinib Alone in Metastatic Renal Cell Carcinoma: A Randomized Phase 2 Study

Lindskog, Magnus; Laurell, Anna; Kjellman, Anders; Melichar, Bohuslav et al.

Part of European Urology Open Science, p. 38-45, 2022.

Article in journal

DOI for Ilixadencel, a Cell-based Immune Primer, plus Sunitinib Versus Sunitinib Alone in Metastatic Renal Cell Carcinoma: A Randomized Phase 2 Study Download full text (pdf) of Ilixadencel, a Cell-based Immune Primer, plus Sunitinib Versus Sunitinib Alone in Metastatic Renal Cell Carcinoma: A Randomized Phase 2 Study

Open access
Cell-lineage controlled epigenetic regulation in glioblastoma stem cells determines functionally distinct subgroups and predicts patient survival

Lu, Xi; Maturi, Naga Prathyusha; Jarvius, Malin; Yildirim, Irem et al.

Part of Nature Communications, 2022.

Article in journal

DOI for Cell-lineage controlled epigenetic regulation in glioblastoma stem cells determines functionally distinct subgroups and predicts patient survival Download full text (pdf) of Cell-lineage controlled epigenetic regulation in glioblastoma stem cells determines functionally distinct subgroups and predicts patient survival

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Sorafenib and nitazoxanide disrupt mitochondrial function and inhibit regrowth capacity in three-dimensional models of hepatocellular and colorectal carcinoma

Nyberg, Frida; Blom, Kristin; Selvin, Tove; Rudfeldt, Jakob et al.

Part of Scientific Reports, 2022.

Article in journal

DOI for Sorafenib and nitazoxanide disrupt mitochondrial function and inhibit regrowth capacity in three-dimensional models of hepatocellular and colorectal carcinoma Download full text (pdf) of Sorafenib and nitazoxanide disrupt mitochondrial function and inhibit regrowth capacity in three-dimensional models of hepatocellular and colorectal carcinoma

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Surgical waiting times and all-cause mortality in patients with non-metastatic renal cell carcinoma

Rosenblad, Andreas; Sundqvist, Pernilla; Harmenberg, Ulrika; Hellström, Mikael et al.

Part of Scandinavian journal of urology, p. 383-390, 2022.

Article in journal

DOI for Surgical waiting times and all-cause mortality in patients with non-metastatic renal cell carcinoma Download full text (pdf) of Surgical waiting times and all-cause mortality in patients with non-metastatic renal cell carcinoma

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Plasma protein biomarker profiling reveals major differences between acute leukaemia, lymphoma patients and controls

Sabaa, Amal Abu; Shen, Qiujin; Lennmyr, Emma; Enblad, Anna Pia et al.

Part of New Biotechnology, p. 21-29, 2022.

Article in journal

DOI for Plasma protein biomarker profiling reveals major differences between acute leukaemia, lymphoma patients and controls Download full text (pdf) of Plasma protein biomarker profiling reveals major differences between acute leukaemia, lymphoma patients and controls

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Single-cell transcriptional pharmacodynamics of trifluridine in a tumor-immune model

Selvin, Tove; Fasterius, Erik; Jarvius, Malin; Fryknäs, Mårten et al.

Part of Scientific Reports, 2022.

Article in journal

DOI for Single-cell transcriptional pharmacodynamics of trifluridine in a tumor-immune model Download full text (pdf) of Single-cell transcriptional pharmacodynamics of trifluridine in a tumor-immune model

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Metabolomics: The Stethoscope for the Twenty-First Century

Ashrafian, Hutan; Sounderajah, Viknesh; Glen, Robert; Ebbels, Timothy et al.

Part of Medical principles and practice, p. 301-310, 2021.

Article in journal

DOI for Metabolomics: The Stethoscope for the Twenty-First Century Download full text (pdf) of Metabolomics: The Stethoscope for the Twenty-First Century

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Multi‐cohort profiling reveals elevated CSF levels of brain‐enriched proteins in Alzheimer’s disease

Bergström, Sofia; Remnestål, Julia; Yousef, Jamil; Olofsson, Jennie et al.

Part of Annals of Clinical and Translational Neurology, p. 1456-1470, 2021.

Article in journal

DOI for Multi‐cohort profiling reveals elevated CSF levels of brain‐enriched proteins in Alzheimer’s disease Download full text (pdf) of Multi‐cohort profiling reveals elevated CSF levels of brain‐enriched proteins in Alzheimer’s disease

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Different Inflammatory Signatures in Alzheimer's Disease and Frontotemporal Dementia Cerebrospinal Fluid

Boström, Gustaf; Freyhult, Eva; Virhammar, Johan; Alcolea, Daniel et al.

Part of Journal of Alzheimer's Disease, p. 629-640, 2021.

Article in journal

DOI for Different Inflammatory Signatures in Alzheimer's Disease and Frontotemporal Dementia Cerebrospinal Fluid Download full text (pdf) of Different Inflammatory Signatures in Alzheimer's Disease and Frontotemporal Dementia Cerebrospinal Fluid

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Melphalan flufenamide inhibits osteoclastogenesis by suppressing proliferation of monocytes

Byrgazov, Konstantin; Lind, Thomas; Rasmusson, Annica J.; Andersson, Claes et al.

Part of Bone Reports, 2021.

Article in journal

DOI for Melphalan flufenamide inhibits osteoclastogenesis by suppressing proliferation of monocytes

Open access
Increased levels of plasma cytokines and correlations to organ failure and 30-day mortality in critically ill Covid-19 patients

Bülow Anderberg, Sara; Luther, Tomas; Berglund, Malin; Larsson, Rolf et al.

Part of Cytokine, 2021.

Article in journal

DOI for Increased levels of plasma cytokines and correlations to organ failure and 30-day mortality in critically ill Covid-19 patients Download full text (pdf) of Increased levels of plasma cytokines and correlations to organ failure and 30-day mortality in critically ill Covid-19 patients

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Conditions for maintenance of hepatocyte differentiation and function in 3D cultures

Handin, Niklas; Mickols, Evgeniya; Ölander, Magnus; Rudfeldt, Jakob et al.

Part of iScience, 2021.

Article in journal

DOI for Conditions for maintenance of hepatocyte differentiation and function in 3D cultures Download full text (pdf) of Conditions for maintenance of hepatocyte differentiation and function in 3D cultures

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DNA Methylation Signatures Predict Cytogenetic Subtype and Outcome in Pediatric Acute Myeloid Leukemia (AML)

Krali, Olga; Palle, J; Bäcklin, Christofer; Abrahamsson, Jonas et al.

Part of Genes, 2021.

Article in journal

DOI for DNA Methylation Signatures Predict Cytogenetic Subtype and Outcome in Pediatric Acute Myeloid Leukemia (AML) Download full text (pdf) of DNA Methylation Signatures Predict Cytogenetic Subtype and Outcome in Pediatric Acute Myeloid Leukemia (AML)

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A phase 2a clinical study on the safety and efficacy of individualized dosed mebendazole in patients with advanced gastrointestinal cancer

Mansoori, Sharmineh; Fryknäs, Mårten; Alvfors, Carina; Loskog, Angelica et al.

Part of Scientific Reports, 2021.

Article in journal

DOI for A phase 2a clinical study on the safety and efficacy of individualized dosed mebendazole in patients with advanced gastrointestinal cancer Download full text (pdf) of A phase 2a clinical study on the safety and efficacy of individualized dosed mebendazole in patients with advanced gastrointestinal cancer

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Challenging conventional karyotyping by next-generation karyotyping in 281 intensively treated patients with AML

Mareschal, Sylvain; Palau, Anna; Lindberg, Johan; Ruminy, Philippe et al.

Part of Blood Advances, p. 1003-1016, 2021.

Article in journal

DOI for Challenging conventional karyotyping by next-generation karyotyping in 281 intensively treated patients with AML

Open access
Plasma proteome profiling of cardiotoxicity in patients with diffuse large B-cell lymphoma

Mörth, Charlott; Sabaa, Amal Abu; Freyhult, Eva; Christersson, Christina et al.

Part of Cardio-Oncology, 2021.

Article in journal

DOI for Plasma proteome profiling of cardiotoxicity in patients with diffuse large B-cell lymphoma Download full text (pdf) of Plasma proteome profiling of cardiotoxicity in patients with diffuse large B-cell lymphoma

Open access
Metabolic drift in the aging nervous system is reflected in human cerebrospinal fluid

Peters, Kristian; Herman, Stephanie; Emami Khoonsari, Payam; Burman, Joachim et al.

Part of Scientific Reports, 2021.

Article in journal

DOI for Metabolic drift in the aging nervous system is reflected in human cerebrospinal fluid Download full text (pdf) of Metabolic drift in the aging nervous system is reflected in human cerebrospinal fluid

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Toll-like receptor 4 methylation grade is linked to depressive symptom severity

Rasmusson, Annica J.; Gallwitz, Maike; Soltanabadi, Bardia; Ciuculete, Diana-Maria et al.

Part of Translational Psychiatry, 2021.

Article in journal

DOI for Toll-like receptor 4 methylation grade is linked to depressive symptom severity Download full text (pdf) of Toll-like receptor 4 methylation grade is linked to depressive symptom severity

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Approaches for containerized scientific workflows in cloud environments with applications in life science

Spjuth, Ola; Capuccini, Marco; Carone, Matteo; Larsson, Anders et al.

Part of F1000 Research, p. 513-513, 2021.

Article in journal

DOI for Approaches for containerized scientific workflows in cloud environments with applications in life science
COVIDENZA - A prospective, multicenter, randomized PHASE II clinical trial of enzalutamide treatment to decrease the morbidity in patients with Corona virus disease 2019 (COVID-19): a structured summary of a study protocol for a randomised controlled trial

Welen, Karin; Overby, Anna K.; Ahlm, Clas; Freyhult, Eva et al.

Part of Trials, 2021.

Article in journal

DOI for COVIDENZA - A prospective, multicenter, randomized PHASE II clinical trial of enzalutamide treatment to decrease the morbidity in patients with Corona virus disease 2019 (COVID-19): a structured summary of a study protocol for a randomised controlled trial Download full text (pdf) of COVIDENZA - A prospective, multicenter, randomized PHASE II clinical trial of enzalutamide treatment to decrease the morbidity in patients with Corona virus disease 2019 (COVID-19): a structured summary of a study protocol for a randomised controlled trial

Open access
Mebendazole is unique among tubulin-active drugs in activating the MEK-ERK pathway

Andersson, Claes; Selvin, Tove; Blom, Kristin; Rubin, Jenny et al.

Part of Scientific Reports, 2020.

Article in journal

DOI for Mebendazole is unique among tubulin-active drugs in activating the MEK-ERK pathway Download full text (pdf) of Mebendazole is unique among tubulin-active drugs in activating the MEK-ERK pathway

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Targeting aggressive osteosarcoma with a peptidase-enhanced cytotoxic melphalan flufenamide

Byrgazov, Konstantin; Andersson, Claes; Salzer, Benjamin; Bozsaky, Eva et al.

Part of THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY, 2020.

Article in journal

DOI for Targeting aggressive osteosarcoma with a peptidase-enhanced cytotoxic melphalan flufenamide Download full text (pdf) of Targeting aggressive osteosarcoma with a peptidase-enhanced cytotoxic melphalan flufenamide

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Chantzi, Efthymia

Algorithmic discovery, development and personalized selection of higher-order drug cocktails: A label-free live-cell imaging & secretomics approach

2020.

Doctoral thesis, comprehensive summary

Download full text (pdf) of Chantzi, Efthymia

Open access
COMBSecretomics: a pragmatic methodological framework for higher-order drug combination analysis using secretomics

Chantzi, Efthymia; Neidlin, Michael; Macheras, George A.; Alexopoulos, Leonidas G. et al.

Part of PLOS ONE, 2020.

Article in journal

DOI for COMBSecretomics: a pragmatic methodological framework for higher-order drug combination analysis using secretomics Download full text (pdf) of COMBSecretomics: a pragmatic methodological framework for higher-order drug combination analysis using secretomics

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Rational Design of Azastatin as a Potential ADC Payload with Reduced Bystander Killing.

Hartmann, Rafael; Fahrner, Raphael; Shevshenko, Denys; Fryknäs, Mårten et al.

Part of ChemMedChem, p. 2500-2512, 2020.

Article in journal

DOI for Rational Design of Azastatin as a Potential ADC Payload with Reduced Bystander Killing. Download full text (pdf) of Rational Design of Azastatin as a Potential ADC Payload with Reduced Bystander Killing.

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Gene Expression Alterations during Development of Castration-Resistant Prostate Cancer Are Detected in Circulating Tumor Cells

Josefsson, Andreas; Larsson, Karin; Freyhult, Eva; Damber, Jan-Erik et al.

Part of Cancers, 2020.

Article in journal

DOI for Gene Expression Alterations during Development of Castration-Resistant Prostate Cancer Are Detected in Circulating Tumor Cells Download full text (pdf) of Gene Expression Alterations during Development of Castration-Resistant Prostate Cancer Are Detected in Circulating Tumor Cells

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Genomic and transcriptomic features of dermatofibrosarcoma protuberans: Unusual chromosomal origin of the COL1A1-PDGFB fusion gene and synergistic effects of amplified regions in tumor development

Koster, Jan; Arbajian, Elsa; Viklund, Björn; Isaksson, Anders et al.

Part of Cancer Genetics, p. 34-41, 2020.

Article in journal

DOI for Genomic and transcriptomic features of dermatofibrosarcoma protuberans: Unusual chromosomal origin of the COL1A1-PDGFB fusion gene and synergistic effects of amplified regions in tumor development Download full text (pdf) of Genomic and transcriptomic features of dermatofibrosarcoma protuberans: Unusual chromosomal origin of the COL1A1-PDGFB fusion gene and synergistic effects of amplified regions in tumor development

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Antibacterial pyrrolidinyl and piperidinyl substituted 2,4-diacetylphloroglucinols from Pseudomonas protegens UP46

Levenfors, Jolanta J.; Nord, Christina; Bjerketorp, Joakim; Stahlberg, Jerry et al.

Part of Journal of antibiotics (Tokyo. 1968), p. 739-747, 2020.

Article in journal

DOI for Antibacterial pyrrolidinyl and piperidinyl substituted 2,4-diacetylphloroglucinols from Pseudomonas protegens UP46
Association between proteomics and obstructive sleep apnea phenotypes in a community-based cohort of women

Ljunggren, Mirjam; Theorell-Haglöw, Jenny; Freyhult, Eva; Sahlin, Carin et al.

Part of Journal of Sleep Research, 2020.

Article in journal

DOI for Association between proteomics and obstructive sleep apnea phenotypes in a community-based cohort of women Download full text (pdf) of Association between proteomics and obstructive sleep apnea phenotypes in a community-based cohort of women

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Prognostic Value of Circulating Microvesicle Subpopulations in Ischemic Stroke and TIA

Lundström, Annika; Mobarrez, Fariborz; Rooth, Elisabeth; Thalin, Charlotte et al.

Part of Translational Stroke Research, p. 708-719, 2020.

Article in journal

DOI for Prognostic Value of Circulating Microvesicle Subpopulations in Ischemic Stroke and TIA Download full text (pdf) of Prognostic Value of Circulating Microvesicle Subpopulations in Ischemic Stroke and TIA

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Microparticles expressing myeloperoxidase as potential biomarkers in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV)

Manojlovic, M.; Juto, A.; Jonasdottir, A.; Colic, J. et al.

Part of Journal of Molecular Medicine, p. 1279-1286, 2020.

Article in journal

DOI for Microparticles expressing myeloperoxidase as potential biomarkers in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV) Download full text (pdf) of Microparticles expressing myeloperoxidase as potential biomarkers in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAV)

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A Novel Multiplex Based Platform for Osteoarthritis Drug Candidate Evaluation

Neidlin, Michael; Chantzi, Efthymia; Macheras, George; Gustafsson, Mats G et al.

Part of Annals of Biomedical Engineering, p. 2438-2448, 2020.

Article in journal

DOI for A Novel Multiplex Based Platform for Osteoarthritis Drug Candidate Evaluation
Isopedopeptins A-H: Cationic Cyclic Lipodepsipeptides from Pedobacter cryoconitis UP508 Targeting WHO Top-Priority Carbapenem-Resistant Bacteria

Nord, Christina; Bjerketorp, Joakim; Levenfors, Jolanta J.; Cao, Sha et al.

Part of ACS Chemical Biology, p. 2937-2944, 2020.

Article in journal

DOI for Isopedopeptins A-H: Cationic Cyclic Lipodepsipeptides from Pedobacter cryoconitis UP508 Targeting WHO Top-Priority Carbapenem-Resistant Bacteria Download full text (pdf) of Isopedopeptins A-H: Cationic Cyclic Lipodepsipeptides from Pedobacter cryoconitis UP508 Targeting WHO Top-Priority Carbapenem-Resistant Bacteria

Open access
Changes in the plasma microvesicle proteome during the ovarian hyperstimulation phase of assisted reproductive technology

Olausson, Nina; Mobarrez, Fariborz; Zubarev, Roman; Chernobrovkin, Alexey et al.

Part of Scientific Reports, 2020.

Article in journal

DOI for Changes in the plasma microvesicle proteome during the ovarian hyperstimulation phase of assisted reproductive technology Download full text (pdf) of Changes in the plasma microvesicle proteome during the ovarian hyperstimulation phase of assisted reproductive technology

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Melflufen for relapsed and refractory multiple myeloma

Oriol, Albert; Larocca, Alessandra; Leleu, Xavier; Hajek, Roman et al.

Part of Expert Opinion on Investigational Drugs, p. 1069-1078, 2020.

Article in journal

DOI for Melflufen for relapsed and refractory multiple myeloma
Elevated inflammatory proteins in cerebrospinal fluid from patients with painful knee osteoarthritis are associated with reduced symptom severity

Palada, Vinko; Ahmed, Aisha Siddiqah; Freyhult, Eva; Hugo, Anders et al.

Part of Journal of Neuroimmunology, 2020.

Article in journal

DOI for Elevated inflammatory proteins in cerebrospinal fluid from patients with painful knee osteoarthritis are associated with reduced symptom severity Download full text (pdf) of Elevated inflammatory proteins in cerebrospinal fluid from patients with painful knee osteoarthritis are associated with reduced symptom severity

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Descriptive Proteome Analysis to Investigate Context-Dependent Treatment Responses to OXPHOS Inhibition in Colon Carcinoma Cells Grown as Monolayer and Multicellular Tumor Spheroids

Steinmetz, Julia; Senkowski, Wojciech; Lengqvist, Johan; Rubin, Jenny et al.

Part of ACS Omega, p. 17242-17254, 2020.

Article in journal

DOI for Descriptive Proteome Analysis to Investigate Context-Dependent Treatment Responses to OXPHOS Inhibition in Colon Carcinoma Cells Grown as Monolayer and Multicellular Tumor Spheroids Download full text (pdf) of Descriptive Proteome Analysis to Investigate Context-Dependent Treatment Responses to OXPHOS Inhibition in Colon Carcinoma Cells Grown as Monolayer and Multicellular Tumor Spheroids

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Phosphatidylserine positive microparticles improve hemostasis in in-vitro hemophilia A plasma models

Zong, Yanan; Pruner, Iva; Antovic, Aleksandra; Taxiarchis, Apostolos et al.

Part of Scientific Reports, 2020.

Article in journal

DOI for Phosphatidylserine positive microparticles improve hemostasis in in-vitro hemophilia A plasma models Download full text (pdf) of Phosphatidylserine positive microparticles improve hemostasis in in-vitro hemophilia A plasma models

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Mebendazole-induced M1 polarisation of THP-1 macrophages may involve DYRK1B inhibition

Blom, Kristin; Rubin, Jenny; Berglund, Malin; Jarvius, Malin et al.

Part of BMC Research Notes, 2019.

Article in journal

DOI for Mebendazole-induced M1 polarisation of THP-1 macrophages may involve DYRK1B inhibition Download full text (pdf) of Mebendazole-induced M1 polarisation of THP-1 macrophages may involve DYRK1B inhibition

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COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining

Chantzi, Efthymia; Jarvius, Malin; Niklasson, Mia; Segerman, Anna et al.

Part of BMC Bioinformatics, 2019.

Article in journal

DOI for COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining Download full text (pdf) of COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining

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Anti-inflammatory drugs with more penetration into the central nervous system may contribute to the treatment of trigeminal neuralgia Reply

Ericson, Hans; Abu Hamdeh, Sami; Freyhult, Eva; Stiger, Fredrik et al.

Part of Pain, p. 2898-2899, 2019.

Article in journal

DOI for Anti-inflammatory drugs with more penetration into the central nervous system may contribute to the treatment of trigeminal neuralgia Reply

Last modified: 2022-06-09