Research projects

Our goal is to improve the treatment and care of the individual patient and to reduce the burden of cardiovascular disease - for the patient and the community.

We conduct research projects in the following areas:

Cardiovascular Disease incidence and long term follow up in national and international clinical registries

• Epidemiological registry and cohort studies including:
  • SWEDEHEART projects
  • EUROHEART projects
  • RIKSSVIKT projects

Registry based randomized clinical trials (R-RCT) to evaluate and implement cardiac care and treatments

• HELP – Cluster R-RCT on Helicobacter pylori screening in patients with myocardial infarction
• DAPA-MI – R-RCT on Dapagliflozin in individuals with a myocardial infarction, and normal ejection fraction of the heart
• INFINITY-SWEDHEART – R-RCT on comparing long term outcomes of the DynamX Bioadaptor to the Resolute Onyx coronary stents
• MINOCA-BAT – optimal medical treatment in patients with MINOCA
• REDUCE-SWEDEHEART – Betablockers in patients with a myocardial infarction, and normal ejection fraction of the heart

Diagnosis, risk assessment and individualized treatment

• Biomarker substudies – in several national and international clinical cohorts
• The ABC-AF project – A study for increased understanding and risk assessment of individuals with atrial fibrillation – including a prospective trial of risk assessment using the ABC-AF risk tool

Pathophysiological studies on imaging and mechanistic studies

• DAPA-CARD - Advanced cardiac imaging of individuals on dapagliflozin treatment
• LV- REGURGE study – A study on long term follow up of Mitral Regurgitation and LV function

Evaluation of new (but also clinically available) therapies

• International pharmaceutical trials – we lead, or take part in, several randomized clinical trials.
• Registry based randomized clinical trials (R-RCT) within the framework of SWEDEHEART and other registries

Observational registry and cohort studies