Department of Medical Sciences

ULSAM: The Uppsala Longitudinal Study of Adult Men

Our group participates actively in genetic studies in the ULSAM cohort. For more information see the ULSAM homepage  (


  • Cornelis MC, et al. (2016) Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior. Hum Mol Genet, 2016 Oct 3 [Epub ahead of print]
  • Golbus JR, et al. (2016) Common and Rare Genetic Variation in CCR2,CCR5, or CX3CR1 and Risk of Atherosclerotic Coronary Heart Disease and Glucometabolic Traits. Circ Cardiovasc Genet 9(3), 250-258
  • Loley C, et al. (2016) No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis. Sci Rep 6:35278
  • Surendran P et al. (2016) Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension. Nat Genet 48(10), 1151-1161
  • Dumanski JP et al. (2015) Smoking is associated with mosaic loss of chromosome Y. Science 347(6217), 81-83
  • Fall T et al. (2015) Age- and Sex-Specific Causal Effects of Adiposity on Cardiovascular Risk Factors. Diabetes 64(5), 1841-1852
  • Locke AE et al. (2015) Genetic studies of body mass index yield new insights for obesity biology. Nature 518(7538), 197-206
  • Shungin D et al, (2015) New genetic loci link adipose and insulin biology to body fat distribution. Nature 518(7538), 187-196
  • Penell J et al. (2014) Genetic variation in the CYP2B6 Gene is related to circulating 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) concentrations: an observational population-based study. Environ Health 13(1), 34
  • Lind L et al. (2014) Genetic variation in the CYP1A1 gene is related to circulating PCB118 levels in a population-based sample. Environ Res133(Aug 2014), 135-140
  • Lind L et al. (2013) Genetic variation in the dimethylarginine dimethylaminohydrolase 1 gene (DDAH1) is related to asymmetric dimethylarginine (ADMA) levels, but not to endothelium-dependent vasodilation. Vasc Med 18(4), 192-199
  • Lind L et al (2013) Variation in genes in the endothelin pathway and endothelium-dependent and independent vasodilation in an elderly population. Acta Physiol 208(1), 88-94
  • Zhu et al. (2011) The Lin28/let-7 axis regulates glucose metabolism. Cell. 147(1):81-94
  • Strawbridge et al. (2011) Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes. Diabetes, 60(10):2624-2634
  • Kanoni et al. (2011) Total Zinc Intake May Modify the Glucose-Raising Effect of a Zinc Transporter (SLC30A8) Variant: A 14-Cohort Meta-analysis. Diabetes 60(9):2407-2416
  • Kilpeläinen et al. (2011) Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Gen, 43:753-760
  • Speliotes et al. (2011)Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits.PLoS Genet. 7(3):e1001324
  • Böger et al. (2011) CUBN Is a Gene Locus for Albuminuria. J Am Soc Nephrol, 22:555-570
  • Heid et al. (2010). Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet, 42(11), 949-960.
  • Dupuis et al. (2010) New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Gen, 42:105-116
  • Ingelsson et al. (2010). Detailed physiologic characterization reveals diverse mechanisms for novel genetic Loci regulating glucose and insulin metabolism in humans. Diabetes, 59(5), 1266-1275.
  • Saxena et al. (2010). Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet, 42(2), 142-148.
  • Nettleton et al. (2010) Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies. Diabetes Care, 33:2684-2691
  • Dahlgren et al. (2008). Association of the Estrogen Receptor 1 (ESR1) Gene with Body Height in Adult Males from Two Swedish Population Cohorts. PLoS ONE, 3(3), e1807
  • Auro et al. (2008) USF1 gene variants contribute to metabolic traits in men in a longitudinal 32-year follow-up study. Diabetologia, 51(3), 464-472