Molecular Precision Medicine research projects

Our research is focused on genomics and epigenomics in human diseases.

Favorite publications from the Molecular Precision Medicine group:

  • Xiao W, Ren L, Chen Z, Fang LT … Nordlund J, Liljedahl U … Wang C, Shi L (2021) Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing. Nat Biotechnol 39 (

  • Krali O, Palle J, Bäcklin C, Abrahamsson J, Norén-Nyström U, Hasle H, Jahnukainen K, Gísli Jónsson Ó, Hovland R, Lausen B, Larsson R, Palmqvist L, Staffas A, Zeller B, Nordlund J (2021) DNA Methylation Signatures Predict Cytogenetic Subtype and Outcome in Pediatric Acute Myeloid Leukemia (AML). Genes 12(6) ( )

  • Duran-Ferrer M, Clot G, Nadeu F, Beekman R, Baumann T, Nordlund J, Marincevic-Zuniga Y, … Campo E, Martin-Subero JI (2020) The proliferative history shapes the DNA methylome of B-cell tumors and predicts clinical outcome Nat Cancer 1 ( 

  • Raine A, Manlig E, Wahlberg P, Syvänen AC, Nordlund J (2017) SPlinted Ligation Adapter Tagging (SPLAT), a novel library preparation method for whole genome bisulphite sequencing. Nucleic Acid Res 45(6), e36 

  • Nordlund J, Bäcklin C, Wahlberg P, Busche S, Berglund E, Eloranta M-L, ... , Sinnett D, Söderhäll S, Pastinen T, Gustafsson M, Lönnerholm G, Syvänen A-C (2013) Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia. Genome Biol 14(9), r105

Review articles & book chapters

Last modified: 2022-05-03